BDBM299537 6-(2-methyl-4- pyridyl)pyrido [3,2-d]pyrimidin- 4-amine::US9592235, Example 307::US9855269, Compound 156

SMILES Cc1cc(ccn1)-c1ccc2ncnc(N)c2n1

InChI Key InChIKey=ISJFCMPYZALBNM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 299537   

LigandPNGBDBM299537(US9592235, Example 307 | 6-(2-methyl-4- pyridyl)py...)
Affinity DataIC50: 50.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/21/2019
Entry Details
US Patent

LigandPNGBDBM299537(US9592235, Example 307 | 6-(2-methyl-4- pyridyl)py...)
Affinity DataIC50: 50.5nMAssay Description:The kinase activity of purified human MAP4K4 kinase domain was measured by monitoring the phosphorylation of a peptide substrate derived from moesin ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent