BDBM299630 (2S,4S)-5-(5′-Chloro-2′-fluorobiphenyl-4-yl)-2-[(2-fluoroethylamino)methyl]-4-[(3H-[1,2,3]triazole-4-carbonyl)amino]pentanoic Acid::US9593110, Example 81::US9593110, Example 82a::US9593110, Example 83b::US9593110, Example 84b::US9593110, Example 85a

SMILES CCOC(=O)[C@H](COS(=O)(=O)c1ccc(C)cc1)C[C@@H](Cc1ccc(cc1)-c1cc(Cl)ccc1F)NB(C)O

InChI Key InChIKey=MQNUYORJAHRKHD-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 299630   

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299630(US9593110, Example 81 | US9593110, Example 85a | (...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299630(US9593110, Example 81 | US9593110, Example 85a | (...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299630(US9593110, Example 81 | US9593110, Example 85a | (...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299630(US9593110, Example 81 | US9593110, Example 85a | (...)
Affinity DataKi: <1nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent

TargetNeprilysin(Human)
Theravence Biopharma R&D Ip

US Patent
LigandPNGBDBM299630(US9593110, Example 81 | US9593110, Example 85a | (...)
Affinity DataKi:  6.60nMAssay Description:Recombinant human NEP and recombinant human ACE were obtained commercially (R&D Systems, Minneapolis, Minn., catalog numbers 1182-ZN and 929-ZN, resp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2019
Entry Details
US Patent