BDBM300179 3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolidin-1-yl)-5-[(3-methyloxetan-3-yl)methoxy]triazolo[4,5-d]pyrimidine::US9593123, Example 50

SMILES CC1(COc2nc(N3CCC(F)(F)C3)c3nnn(Cc4ccccc4Cl)c3n2)COC1

InChI Key InChIKey=ZXCDKKBGLVDLLN-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300179   

TargetCannabinoid receptor 2(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300179(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50:  2.80nMAssay Description:CHO cells expressing human CB1 or CB2 receptors are seeded 17-24 hours prior to the experiment 50.000 cells per well in a black 96 well plate with fl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent

TargetCannabinoid receptor 1(Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM300179(3-[(2-Chlorophenyl)methyl]-7-(3,3-difluoropyrrolid...)
Affinity DataEC50: >1.00E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/15/2019
Entry Details
US Patent