BDBM300842 2-(1-(4-((3-(4-(1,1-Dioxido-1- thia-6-azaspiro[3.3] heptan-6-yl)-2- methylphenyl)benzo[b]thiophen- 5-yl)methoxy)phenyl)-3- oxocyclobutyl)acetic acid::US10131648, Compound 40::US10195178, Compound 40::US9790198, Compound 40

SMILES Cc1cc(ccc1-c1csc2ccc(COc3ccc(cc3)C3(CC(O)=O)CC(=O)C3)cc12)N1CC2(CCS2(=O)=O)C1

InChI Key InChIKey=TUVBOGCWNGIIQN-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 300842   

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300842(2-(1-(4-((3-(4-(1,1-Dioxido-1- thia-6-azaspiro[3.3...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300842(2-(1-(4-((3-(4-(1,1-Dioxido-1- thia-6-azaspiro[3.3...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2019
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM300842(2-(1-(4-((3-(4-(1,1-Dioxido-1- thia-6-azaspiro[3.3...)
Affinity DataEC50:  15nMAssay Description:Compounds were tested in a calcium flux assay using transfected HEK293 cells stably expressing either human GPR40 or rat GPR40. Human GPR40 expressin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2019
Entry Details
US Patent