BDBM300905 (2S,3R)-3-cyclopropyl-3-((RS)-2-(4-(5-fluoro-2-methoxypyridin-4-yl)phenyl)-2,3,4,5-tetrahydrobenzo[b]oxepin-8-yl)-2-methylpropanoic acid::BDBM300906::US10131651, Example 5

SMILES COc1cc(c(F)cn1)-c1ccc(cc1)C1CCCc2ccc(cc2O1)[C@@H]([C@H](C)C(O)=O)C1CC1

InChI Key InChIKey=IOEBRSVWRAVYKP-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 300905   

TargetFree fatty acid receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM300905(US10131651, Example 5 | (2S,3R)-3-cyclopropyl-3-((...)
Affinity DataEC50:  3.10nMAssay Description:The assay is performed in 384-well format. HEK cells stably expressing human GPR40 are plated at 15,000 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent

TargetFree fatty acid receptor 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM300905(US10131651, Example 5 | (2S,3R)-3-cyclopropyl-3-((...)
Affinity DataEC50:  5.20nMAssay Description:The assay is performed in 384-well format. HEK cells stably expressing human GPR40 are plated at 15,000 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2019
Entry Details
US Patent