BDBM301022 4-[1-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6-yl]methyl]-5- (4-methylphenyl)pyrazolo[4,3- b]pyridin-6-yl]benzonitrile::US10131664, Example 15

SMILES Cc1ccc(cc1)-c1nc2cnn(C[C@H]3[C@@H]4CNC[C@H]34)c2cc1-c1ccc(cc1)[N+]#[C-]

InChI Key InChIKey=PXIQKCNNPHGNHB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301022   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM301022(4-[1-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6-yl]meth...)
Affinity DataIC50: 10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent