BDBM301054 4-[3-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6- yl]methylamino]-5-(4- methylphenyl)pyrazol-1-yl]benzonitrile::US10131664, Example 47

SMILES Cc1ccc(cc1)-c1cc(NC[C@H]2[C@@H]3CNC[C@H]23)nn1-c1ccc(cc1)[N+]#[C-]

InChI Key InChIKey=CDDZEZRJVAVOPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301054   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM301054(4-[3-[[(1S,5R)-3- azabicyclo[3.1.0]hexan-6- yl]met...)
Affinity DataIC50: 10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
US Patent