BDBM301058 4-{1-[((3S)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4- methoxyphenyl)pyrrolo[3,2-b]pyridin- 6-yl}benzenecarbonitrile::US10131664, Example 51

SMILES COc1ccc(cc1F)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(cc1)C#N

InChI Key InChIKey=LWGMFZJKYFASHV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301058   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM301058(4-{1-[((3S)pyrrolidin-3-yl)methyl]-5- (3-fluoro-4-...)
Affinity DataIC50: 10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent