BDBM301061 4-[5-morpholin-4-yl-1-[[(3R)- pyrrolidin-3-yl]methyl]pyrrolo[3,2- b]pyridin-6-yl]benzonitrile::US10131664, Example 54

SMILES COc1ccc(cc1)-c1nc2ccn(C[C@H]3CCNC3)c2cc1-c1ccc(C#N)c(F)c1

InChI Key InChIKey=YKBRXFRVZCMNTG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301061   

TargetLysine-specific histone demethylase 1A(Human)
Celgene Quanticel Research

US Patent
LigandPNGBDBM301061(4-[5-morpholin-4-yl-1-[[(3R)- pyrrolidin-3-yl]meth...)
Affinity DataIC50: 10nMAssay Description:The enzymatic assay of LSD1 activity is based on Time Resolved-Fluorescence Resonance Energy Transfer (TR-FRET) detection. The inhibitory properties ...More data for this Ligand-Target Pair
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Date in BDB:
3/29/2019
Entry Details
US Patent