BDBM301283 3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetrahydro-2H-pyrazolo[4'',3'':5,6]pyrido[4,3-d]pyrimidin-2-one::BDBM301287::US10131667, Example 99::US11053246, Example 99::US9611267, Example 99

SMILES COc1cc(OC)c(F)c(N2Cc3cnc4[nH]ncc4c3NC2=O)c1F

InChI Key InChIKey=NUAOTQQBUWYKAJ-UHFFFAOYSA-N

Data  12 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 301283   

TargetFibroblast growth factor receptor 2(Human)
Incyte Holdings

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

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Date in BDB:
4/29/2019
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/29/2019
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Incyte Holdings

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Incyte Holdings

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
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Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/13/2022
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/29/2019
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMAssay Description:The inhibitor potency of the exemplified compounds was measured in an enzyme assay that measures peptide phosphorylation using FRET measurements to d...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 2(Human)
Incyte Holdings

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Incyte

US Patent

LigandBDBM301283(3-(2,6-difluoro-3,5-dimethoxyphenyl)-1,3,4,7-tetra...)Copy SMILESCopy InChI

Affinity DataIC50: 100nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/29/2019
Entry Details
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