BDBM301805 N-(2-((4-cyanobenzyl)amino)ethyl)-N-cyclohexyl-((3,4-dichlorophenethyl)amino)propanamide::US9598381, 7

SMILES CC(NCCc1ccc(Cl)c(Cl)c1)C(=O)N(CCNCc1ccc(cc1)C#N)C1CCCCC1

InChI Key InChIKey=QQTPAZPRDNTYJB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301805   

TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

US Patent
LigandPNGBDBM301805(N-(2-((4-cyanobenzyl)amino)ethyl)-N-cyclohexyl-((3...)
Affinity DataIC50: 1.60E+4nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent