BDBM301813 N-cyclohexyl-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro-2H-benzo[b][1,4]oxazin-8-yl)ethyl)amino)ethyl)-3-methoxypropanamide::US9598381, 10

SMILES COCCC(=O)N(CCNCCc1ccc(O)c2NC(=O)COc12)C1CCCCC1

InChI Key InChIKey=OSVDJOYBXAHAAI-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301813   

TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

US Patent
LigandPNGBDBM301813(N-cyclohexyl-N-(2-((2-(5-hydroxy-3-oxo-3,4-dihydro...)
Affinity DataIC50: 5.00E+4nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent