BDBM301815 N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(2-(4-(indolin-4-yl)piperazin-1-yl)ethyl)propanamide::US9598381, 12

SMILES Clc1ccc(CCNCCC(=O)N(CCN2CCN(CC2)c2cccc3NCCc23)C2CCCCC2)cc1Cl

InChI Key InChIKey=UDXCOWSVDXHHJK-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301815   

TargetN-lysine methyltransferase SMYD2(Human)
Abbvie

US Patent
LigandPNGBDBM301815( N-cyclohexyl-3-((3,4-dichlorophenethyl)amino)-N-(...)
Affinity DataIC50: 9.83E+3nMAssay Description:Binding affinity of compounds having formula (I) to SMYD2 is indicia of their inhibition of the activity of this protein lysine methyltransferase. To...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent