BDBM301980 3-(3-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperazin-1-yl)propyl)-1H-indole-5-carbonitrile::US9598401, Example 34

SMILES FC(F)(F)c1ccnc(n1)N1CCN(CCCc2c[nH]c3ccc(cc23)[N+]#[C-])CC1

InChI Key InChIKey=VPOBWDMIYVMIII-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 301980   

Target5-hydroxytryptamine receptor 1A(Human)
Sunshine Lake Pharma

US Patent
LigandPNGBDBM301980(3-(3-(4-(4-(Trifluoromethyl)pyrimidin-2-yl)piperaz...)
Affinity DataKi:  0.200nMAssay Description:Human HEK-293 cell homogenates (36 μg protein) were incubated at 22° C. for 60 minutes with 0.3 nM [3H]8-OH-DPAT (Perkin-Elmer) in the absence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent