BDBM302231 BDBM302232::US9598415, 143

SMILES CCS(=O)(=O)c5ccc(CNc4nc3cnc(c1c(OC)ncnc1C2CC2)nc3n(C(C)C)c4=O)cc5

InChI Key InChIKey=CACCJVVDPSOKKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302231   

TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM302231(BDBM302232 | US9598415, 143)
Affinity DataIC50: 134nMAssay Description:A nuclear receptor transactivation assay is performed to quantitate the ability of test compounds to inhibit RORγ transactivation of a luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM302231(BDBM302232 | US9598415, 143)
Affinity DataIC50: 162nMAssay Description:A nuclear receptor transactivation assay is performed to quantitate the ability of test compounds to inhibit RORγ transactivation of a luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent