BDBM302245 US9598415, 157

SMILES CCS(=O)(=O)c6ccc(CNc5nc3cnc(c1c(OC)ncnc1C2CC2)nc3n([C@@H](C)C4CC4)c5=O)cn6

InChI Key InChIKey=JAKYSJAPUATEJP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 302245   

TargetNuclear receptor ROR-gamma(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM302245(US9598415, 157)
Affinity DataIC50: 92nMAssay Description:A nuclear receptor transactivation assay is performed to quantitate the ability of test compounds to inhibit RORγ transactivation of a luciferas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent