BDBM302902 ((3-acetyl-1-(2- ((2S,4R)-2-(2'-chloro- 2-fluorobiphenyl-3- ylcarbamoyl)-4- fluoropyrrolidin-1-yl)- 2-oxoethyl)-1H-indol- 5-yl)(pyrimidin-5- yl)amino)methylpivalate::US10660876, Cmpd No. 15::US9598446, Compound 15

SMILES CC(=O)c1cn(CC(=O)N2C[C@H](F)C[C@H]2C(=O)Nc2cccc(c2F)-c2ccccc2Cl)c2ccc(cc12)N(COC(=O)C(C)(C)C)c1cncnc1

InChI Key InChIKey=GNZMPALPIWBMBP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 302902   

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM302902(((3-acetyl-1-(2- ((2S,4R)-2-(2'-chloro- 2-fluorobi...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human Factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2021
Entry Details
US Patent

TargetComplement factor D(Human)
Achillion Pharmaceuticals

US Patent
LigandPNGBDBM302902(((3-acetyl-1-(2- ((2S,4R)-2-(2'-chloro- 2-fluorobi...)
Affinity DataIC50: 5.50E+3nMAssay Description:Human factor D (purified from human serum, Complement Technology, Inc.) at 80 nM final concentration is incubated with test compound at various conce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent