BDBM3030 4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo[3,4-d]pyrimidin-3-amine::4-(Phenylamino)pyrazolo[3,4-d]pyrimidine deriv. 31

SMILES Clc1cccc(Nc2[nH]nc3ncnc(Oc4cccc(Cl)c4)c23)c1

InChI Key InChIKey=PDMAVKGRERGACM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 3030   

TargetEpidermal growth factor receptor(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3030(4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo...)
Affinity DataIC50:  2.42E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Bovine)
Novartis Pharmaceuticals

LigandPNGBDBM3030(4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo...)
Affinity DataIC50: >1.00E+5nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Novartis Pharmaceuticals

LigandPNGBDBM3030(4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase transforming protein Abl(Abelson murine leukemia virus)
Novartis Pharmaceuticals

LigandPNGBDBM3030(4-(3-chlorophenoxy)-N-(3-chlorophenyl)-1H-pyrazolo...)
Affinity DataIC50: >1.00E+4nMAssay Description:IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-32P] labe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed