BDBM303216 US10137122, Compound 95

SMILES Cc1[nH]nc2NC3=C(C(=O)CC(C)(C)C3)C(C)(c12)c1cccc(c1)C#N

InChI Key InChIKey=VBNZFZAQEPPDEF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303216   

TargetGlycogen synthase kinase-3 alpha(Human)
The Broad Institute

US Patent
LigandPNGBDBM303216(US10137122, Compound 95)
Affinity DataIC50: 100nMAssay Description:A solution of 4× inhibitor (5 μL), 4× substrate/ATP-Metal solution (5 μL), and 2× Kinase solution (10 μL) was prepared with assay buff...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent