BDBM303266 2-amino-8-methoxy-N- [(5-methyl-4-phenyl- oxazol-2- yl)methyl]quinazoline-4- carboxamide::US10138212, Example 31

SMILES COc1cccc2c(nc(N)nc12)C(=O)NCc1nc(c(C)o1)-c1ccccc1

InChI Key InChIKey=HFFRWDPLDNMZDI-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303266   

TargetAdenosine receptor A2a(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM303266(2-amino-8-methoxy-N- [(5-methyl-4-phenyl- oxazol-2...)
Affinity DataKi:  1.60nMAssay Description:Binding affinities of compounds of the invention for the human A2a receptor were determined in a competition binding assay using Scintillation Proxim...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent