BDBM303571 US10138229, Example 83::US10875852, Example 83

SMILES CC#CC(=O)N1CCC2(CC(C2)n2nc(c(C(N)=O)c2N)-c2ccc(Oc3ccccc3)cc2)CC1

InChI Key InChIKey=DTNZWLUSVDQGNA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303571   

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303571(US10138229, Example 83 | US10875852, Example 83)
Affinity DataIC50: 2.10nMAssay Description:TBDAn HTRF assay (Cisbio KinEASE-TK cat #62TKOPEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Boehringer Ingelheim International

US Patent
LigandPNGBDBM303571(US10138229, Example 83 | US10875852, Example 83)
Affinity DataIC50: 2.10nMAssay Description:An HTRF assay (Cisbio KinEASE-TK cat #62TK0PEC) was performed to quantitate the ability of test compounds to inhibit BTK mediated phosphorylation of ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2021
Entry Details
US Patent