BDBM303669 N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-5- oxo-1-[4-(1- piperidylmethyl)phenyl] pyrrolidine-3- carboxamide::US10138230, Example F99

SMILES Clc1ccc(CCc2nnc(NC(=O)C3CN(C(=O)C3)c3ccc(CN4CCCCC4)cc3)s2)cc1

InChI Key InChIKey=MQCZDURPEYNVQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303669   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303669(N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-...)
Affinity DataIC50: 2nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent