BDBM303676 N-[5-(2-cyclohexylethyl)- 1,3,4-thiadiazol-2-yl]-5- oxo-1-[4-(1- piperidylmethyl)phenyl] pyrrolidine-3- carboxamide::US10138230, Example F106

SMILES O=C(Nc1nnc(CCC2CCCCC2)s1)C1CN(C(=O)C1)c1ccc(CN2CCCCC2)cc1

InChI Key InChIKey=UAAAEIJUAFBWTL-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303676   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303676(N-[5-(2-cyclohexylethyl)- 1,3,4-thiadiazol-2-yl]-5...)
Affinity DataIC50: 3nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent