BDBM303691 N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-2-yl]-1- [4- (morpholinomethyl) phenyl]-5-oxo- pyrrolidine- 3-carboxamide::US10138230, Example F121

SMILES Clc1ccc(CCc2nnc(NC(=O)C3CN(C(=O)C3)c3ccc(CN4CCOCC4)cc3)s2)cc1

InChI Key InChIKey=DSOWBRKRKUDOAF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 303691   

TargetAutotaxin(Human)
Cancer Research Technology

US Patent
LigandPNGBDBM303691(N-[5-[2-(4- chlorophenyl)ethyl]- 1,3,4-thiadiazol-...)
Affinity DataIC50: 4nMAssay Description:Measuring ATX activity using an enzyme coupled Quanta Red assay (Thermo Scientific Pierce Protein Research Products, Product #15159) was determined a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent