BDBM303786 4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[3,4-e][3]benzazocin-3(2H)-yl)acetyl]amino}benzoic acid::US10138236, Example 4

SMILES OC(=O)c1ccc(NC(=O)Cn2cc3c(cc2=O)-c2cc(Cl)ccc2CCNC3=O)cc1

InChI Key InChIKey=YHCVQIPIKWVWDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303786   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM303786(4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[...)
Affinity DataIC50: 720nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM303786(4-{[(11-Chloro-2,5-dioxo-5,6,7,8-tetrahydropyrido[...)
Affinity DataIC50: 1.80E+4nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent