BDBM303813 2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,8-tetrahydropyrido[3,4-e][3]benzazocin-3(2H)-yl]-4-methoxy-N-(2-methyl-2H-indazol-5-yl)butanamide (Stereoisomer Mixture)::US10138236, Example 31

SMILES COCCC(C(=O)Nc1ccc2nn(C)cc2c1)n1cc2c(cc1=O)-c1cc(Cl)ccc1CC(CF)NC2=O

InChI Key InChIKey=WTECJQOPSGZRRS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 303813   

TargetCoagulation factor XI(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM303813(2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,8-te...)
Affinity DataIC50: 2.80nMAssay Description:The factor XIa inhibition of the substances according to the invention is determined using a biochemical test system which utilizes the reaction of a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent

TargetPlasma kallikrein(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM303813(2-[11-Chloro-7-(fluoromethyl)-2,5-dioxo-5,6,7,8-te...)
Affinity DataIC50: 42nMAssay Description:o determine the plasma kallikrein inhibition of the substances according to the invention, a biochemical test system is used which utilizes the react...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
US Patent