BDBM30388 piperidinyl glycine derivative, 25d

SMILES CCN(CC)C(=O)N1CCC(CC1)[C@@H](NS(=O)(=O)c1ccc(s1)-c1ccc(OC)cc1)C(O)=O

InChI Key InChIKey=KHZOOCSTBFXVQU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 30388   

TargetCollagenase 3(Human)
Novartis

LigandPNGBDBM30388(piperidinyl glycine derivative, 25d)
Affinity DataIC50: 2.80nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Novartis

LigandPNGBDBM30388(piperidinyl glycine derivative, 25d)
Affinity DataIC50: 2.30E+3nMT: 2°CAssay Description:Test compounds were serially diluted in the assay buffer. In each well of a 96-well microtiter plate (Immunofluor B, Dynatech), the inhibitor solutio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/6/2009
Entry Details Article
PubMed