BDBM304680 (4-((R)-4-(((1r,4R)-4-isopropylcyclohexyl)methyl)-3-phenylpiperazin-1-yl)-2-(methylsulfonyl)phenyl)methanol::US10144715, Compound 48-78

SMILES CC(C)C1CCC(C(=O)N2CCN(c3ccc(CCO)c(S(C)(=O)=O)c3)C[C@H]2c2ccccc2)CC1

InChI Key InChIKey=HXTCYOBQTHVZMG-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304680   

TargetOxysterols receptor LXR-beta(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304680BDBM304680((4-((R)-4-(((1r,4R)-4-isopropylcyclohexyl)methyl)-...)
Affinity DataKi:  2.46E+3nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent

TargetOxysterols receptor LXR-alpha(Human)
Vitae Pharmaceuticals

US Patent
LigandChemical structure of BindingDB Monomer ID 304680BDBM304680((4-((R)-4-(((1r,4R)-4-isopropylcyclohexyl)methyl)-...)
Affinity DataKi:  3.07E+4nMAssay Description:Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent