BDBM304766 (3R)-3-(1,4-dimethyl-1H-1,2,3-benzotriazol-5-yl)-3-{4-methyl-3-[(N-methylbenzenesulfonamido)methyl]phenyl}propanoic acid::US10144731, Example 55

SMILES CN(Cc1cc(ccc1C)[C@@H](CC(O)=O)c1ccc2n(C)nnc2c1C)S(=O)(=O)c1ccccc1

InChI Key InChIKey=RZDVYTYOVMEPBY-HSZRJFAPSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 304766   

TargetKelch-like ECH-associated protein 1 [321-609](Human)
Glaxosmithkline

US Patent
LigandPNGBDBM304766((3R)-3-(1,4-dimethyl-1H-1,2,3-benzotriazol-5-yl)-3...)
Affinity DataIC50:  55nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNuclear factor erythroid 2-related factor 2(Human)
Glaxosmithkline

US Patent
LigandPNGBDBM304766((3R)-3-(1,4-dimethyl-1H-1,2,3-benzotriazol-5-yl)-3...)
Affinity DataEC50:  5.50E+3nMAssay Description:NAD(P)H:quinone oxidoreductase 1 (NQO1), also called DT diaphorase, is a homodimeric FAD-containing enzyme that catalyzes obligatory NAD(P)H-dependen...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent