BDBM304974 3-(1,4-dimethyl-1H-benzo[d][1,2,3]triazol-5-yl)-3-(3-((1,1-dioxido-3,4-dihydro-2H-pyrido[4,3-b][1,4,5]oxathiazepin-2-yl)methyl)-4-methylphenyl)propanoic acid::US10144731, Example 70

SMILES Cc1ccc(cc1CN1CCOc2ccncc2S1(=O)=O)C(CC(O)=O)c1ccc2n(C)nnc2c1C

InChI Key InChIKey=KHKRJIKQDOFQIX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304974   

TargetKelch-like ECH-associated protein 1 [321-609](Human)
Glaxosmithkline

US Patent
LigandPNGBDBM304974(US10144731, Example 70 | 3-(1,4-dimethyl-1H-benzo[...)
Affinity DataIC50: 55nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent