BDBM304978 3-(4-chloro-3-(((R)-4-methyl-1,1-dioxido-3,4-dihydro-2H-benzo[b][1,4,5]oxathiazepin-2-yl)methyl)phenyl)-3-(1-methyl-2-oxo-1,2-dihydropyridin-4-yl)propanoic acid::US10144731, Example 85

SMILES C[C@@H]1CN(Cc2cc(ccc2Cl)C(CC(O)=O)c2ccn(C)c(=O)c2)S(=O)(=O)c2ccccc2O1

InChI Key InChIKey=YZJHIJHDIPVFFH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 304978   

TargetKelch-like ECH-associated protein 1 [321-609](Human)
Glaxosmithkline

US Patent
LigandPNGBDBM304978(US10144731, Example 85 | 3-(4-chloro-3-(((R)-4-met...)
Affinity DataIC50: 55nMAssay Description:100 nL of 100× compound dose response curves (serial 3-fold dilutions) in DMSO are stamped using an Echo liquid handling system (Labcyte) into 384-we...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2019
Entry Details
US Patent