BDBM306528 (+-)-N-[(4-carbamimidoylphenyl) methyl]-12-(2,4- difluorophenyl)-15-oxatetracyclo [6.6.1.02,7.09,14]-pentadeca- 2,4,6,9,11,13-hexaene- 4-carboxamide::US10144746, Compound 170

SMILES NC(=N)c1ccc(CNC(=O)c2ccc3C4OC(c3c2)c2cc(ccc42)-c2ccc(F)cc2F)cc1

InChI Key InChIKey=AOLAUOFUQJVDKZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 306528   

TargetPlasma kallikrein(Human)
Global Blood Therapeutics

US Patent
LigandPNGBDBM306528(US10144746, Compound 170 | (+-)-N-[(4-carbamimidoy...)
Affinity DataIC50: 1nMAssay Description:The chromogenic substrate D-Pro-Phe-Arg-pNa, 2HCl (BIOPHEN CS-31(02) from Hyphen BioMed, Neuville-Sur-oise, France) was dissolved in 5 mL deionized w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent