BDBM30717 1-(3-benzyl-2-imino-benzimidazol-1-yl)-3-phenoxy-propan-2-ol;hydrochloride::1-(3-benzyl-2-iminobenzimidazol-1-yl)-3-phenoxypropan-2-ol;hydrochloride::1-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl]-3-phenoxy-propan-2-ol;hydrochloride::1-[2-imino-3-(phenylmethyl)-1-benzimidazolyl]-3-phenoxy-2-propanol;hydrochloride::CHEMBL1196297::MLS000039000::SMR000035350::cid_2858173

SMILES OC(COc1ccccc1)Cn1c2ccccc2n(Cc2ccccc2)c1=N

InChI Key InChIKey=YLKDCSKJNOKCGZ-UHFFFAOYSA-N

Data  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 30717   

TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Vanderbilt Screening Center For Gpcrs, Ion Channels and Transporters

Curated by PubChem BioAssay
LigandPNGBDBM30717(1-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl...)
Affinity DataEC50:  2.60E+3nMAssay Description:Assay Provider: Xinmin Xie Assay Provider Affiliation: Bioscience Division, SRI International, Menlo Park, CA Grant Title: HTS Assay for Cav3 T-Type ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/1/2011
Entry Details
PCBioAssay
TargetSodium/glucose cotransporter 2(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM30717(1-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl...)
Affinity DataEC50:  4.60E+3nMAssay Description:Inhibition of human SGLT2 expressed in CHO-K1 cells assessed as reduction in [14C]-alpha-methylglucopyranoside uptake after 2 hrs by liquid scintilla...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM30717(1-[2-azanylidene-3-(phenylmethyl)benzimidazol-1-yl...)
Affinity DataEC50:  9.90E+4nMpH: 7.4 T: 2°CAssay Description:A cell line containing the human 5-HT1a receptor, the promiscuous G-alpha-15 protein (Ga15) as well as the beta-lactamase (BLA) reporter-gene under c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay