BDBM307546 5-(6-Ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)benzofuran-5-yl)-2-methoxy-N-(1-(pyrimidin-2-yl)cyclopropyl)nicotinamide::US10150747, Example 13

SMILES CCOc1cc2oc(c(C(=O)NC)c2cc1-c1cnc(OC)c(c1)C(=O)NC1(CC1)c1ncccn1)-c1ccc(F)cc1

InChI Key InChIKey=QUAXDCWZWDIIIK-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307546   

TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307546(5-(6-Ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)...)
Affinity DataEC50:  3.67nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGenome polyprotein(Hepatitis C virus (HCV))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM307546(5-(6-Ethoxy-2-(4-fluorophenyl)-3-(methylcarbamoyl)...)
Affinity DataIC50:  2.72nMAssay Description:To evaluate compound efficacy, titrated compounds were transferred to sterile 384-well tissue culture treated plates, and the plates were seeded with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent