BDBM307603 ((2R,4R)-4-((3-Methoxypyridin-2- yl)amino)-2-methylpyrrolidin-1-yl)(2- (5-methyl-1,2,4-oxadiazol-3- yl)phenyl)methanone::US10150751, Example 42

SMILES COc1cccnc1N[C@@H]1C[C@@H](C)N(C1)C(=O)c1ccccc1-c1noc(C)n1

InChI Key InChIKey=LJZGWJDJMAPPJL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 307603   

TargetOrexin receptor type 2(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM307603(US10150751, Example 42 | ((2R,4R)-4-((3-Methoxypyr...)
Affinity DataIC50: 500nMAssay Description: All reagents were from GIBCO-Invitrogen Corp. The seeded plates are incubated overnight at 37° C. and 5% CO2. Ala-6,12 human orexin-A as the agonist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent

TargetOrexin/Hypocretin receptor type 1(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM307603(US10150751, Example 42 | ((2R,4R)-4-((3-Methoxypyr...)
Affinity DataIC50: 1.00E+4nMAssay Description: All reagents were from GIBCO-Invitrogen Corp. The seeded plates are incubated overnight at 37° C. and 5% CO2. Ala-6,12 human orexin-A as the agonist...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent