BDBM307632 2-(6-(4-cyclopropyl- 4H-1,2,4-triazole-3- yl)pyridin-2-yl)-5- (thiomorpholine-4- carbonyl)isoindolin- 1-one::US10150755, Compound 24

SMILES O=C(N1CCSCC1)c1ccc2C(=O)N(Cc2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key InChIKey=JSKGIOIFNNBQGD-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307632   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Seal Rock Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 307632BDBM307632(US10150755, Compound 24 | 2-(6-(4-cyclopropyl- 4H-...)
Affinity DataIC50: 200nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent