BDBM307657 6-(4-chloropyridin- 3-yl)-2-(6-(4- cyclopropyl-4H- 1,2,4-triazol-3- yl)pyridin-2- yl)isoindolin-1-one::US10150755, Compound 49

SMILES Clc1ccncc1-c1ccc2CN(C(=O)c2c1)c1cccc(n1)-c1nncn1C1CC1

InChI Key InChIKey=FWOZCZAMWBBXGX-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307657   

TargetMitogen-activated protein kinase kinase kinase 5(Human)
Seal Rock Therapeutics

US Patent
LigandChemical structure of BindingDB Monomer ID 307657BDBM307657(US10150755, Compound 49 | 6-(4-chloropyridin- 3-yl...)
Affinity DataIC50: 200nMAssay Description:The ASK1 enzymatic assay was run following Promega ASK1 Kinase Enzyme System (Cat #V3881). The kit provides the protocol, enzymes and all reagents ne...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2019
Entry Details
US Patent