BDBM307733 (3R)-N-[4-(1-benzyl-3-benzyl-3-cyano-1H-indol-6-yl)-5-chloropyridin-2-yl]piperidine-3-carboxamide::US9650358, Example 29

SMILES Clc1cnc(NC(=O)[C@@H]2CCCNC2)cc1-c1ccc2c(c1)N(Cc1ccccc1)CC2(Cc1ccccc1)C#N

InChI Key InChIKey=MDFQPGPFQXABSH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307733   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM307733(US9650358, Example 29 | (3R)-N-[4-(1-benzyl-3-ben...)
Affinity DataIC50: 12nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent