BDBM307737 (3R)-N-{5-chloro-4-[1-(3-fluorobenzyl)-1H-pyrrolo[3,2-b]pyridin-6-yl]pyridin-2-yl}piperidine-3-carboxamide::US9650358, Example 33

SMILES Fc1cccc(Cn2ccc3ncc(cc23)-c2cc(NC(=O)[C@@H]3CCCNC3)ncc2Cl)c1

InChI Key InChIKey=DXPLKIIPZMKOLA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 307737   

TargetCyclin-dependent kinase 9(Human)
Abbvie

US Patent
LigandPNGBDBM307737(US9650358, Example 33 | (3R)-N-{5-chloro-4-[1-(3-...)
Affinity DataIC50: 14nMAssay Description:CDK9 enzyme activities were measured using LANCE ULight TR-FRET kinase assay reagents (PerkinElmer, Waltham, Mass.). Compounds were directly added in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent