BDBM308226 US9649309, Compound UNC4103A

SMILES CCCCNc1ncc(-c2ccc(CNCC34CC5CC(CC(C5)C3)C4)cn2)c(N[C@H]2CC[C@H](O)CC2)n1

InChI Key InChIKey=GMAFXYZWTSGYMU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 308226   

TargetReceptor-type tyrosine-protein kinase FLT3(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 308226BDBM308226(US9649309, Compound UNC4103A)
Affinity DataIC50: 0.420nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase Mer(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 308226BDBM308226(US9649309, Compound UNC4103A)
Affinity DataIC50: 0.430nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetGrowth arrest-specific protein 6(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 308226BDBM308226(US9649309, Compound UNC4103A)
Affinity DataIC50: 1.30nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent

TargetTyrosine-protein kinase receptor TYRO3(Human)
University of North Carolina at Chapel Hill

US Patent
LigandChemical structure of BindingDB Monomer ID 308226BDBM308226(US9649309, Compound UNC4103A)
Affinity DataIC50: 4.40nMAssay Description:Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/3/2019
Entry Details
US Patent