BDBM309510 N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfonyl]amino}phenyl)thiophene-2-sulfonamide::US9603834, 10::US9603834, 9

SMILES Fc1c(Cl)cccc1S(=O)(=O)Nc1cc(Cl)c(Cl)cc1NS(=O)(=O)c1cccs1

InChI Key InChIKey=SHLQEFPZZAVYHO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 309510   

TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50: 217nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent

TargetC-C chemokine receptor type 2(Human)
Allergan

US Patent
LigandPNGBDBM309510(N-(4,5-dichloro-2-{[(3-chloro-2-fluorophenyl)sulfo...)
Affinity DataIC50: 391nMAssay Description:HEK-Gqi5 cells stably expressing CCR2 were cultured in (DMEM high glucose, 10% FBS, 1% PSA, 400 μg/ml geneticin and 50 μg/ml hygromycin. Ap...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2019
Entry Details
US Patent