BDBM309999 (S)-3-(1-((6-amino-5-(5-methyl-1,3,4-oxadiazol-2-yl)pyrimidin-4-yl)amino)ethyl)-8-chloro-2-cyclopropylisoquinolin-1(2H)-one::US9657007, Example 4

SMILES CC[C@H](Nc1ncnc(N)c1-c1nnc(C)o1)c1cc2cccc(Cl)c2c(=O)n1C1CC1

InChI Key InChIKey=QUXXMGVUUAMKQT-HNNXBMFYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 309999   

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha(Human)
Calitor Sciences

US Patent
LigandPNGBDBM309999((S)-3-(1-((6-amino-5-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  1.47E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM309999((S)-3-(1-((6-amino-5-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  387nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM309999((S)-3-(1-((6-amino-5-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  11nMAssay Description:Kinase assays can be performed by measurement of incorporation of γ-33P ATP into immobilized myelin basic protein (MBP). High binding white 384 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

LigandPNGBDBM309999((S)-3-(1-((6-amino-5-(5-methyl-1,3,4-oxadiazol-2-y...)
Affinity DataIC50:  30nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent