BDBM310220 US10150759, Compound 2

SMILES CC(C)n1ncc2c(cc(nc12)C1CC(C)(C)NC(C)(C)C1)C(=O)NCc1c(C)[nH]c(C)cc1=O

InChI Key InChIKey=PBRRVMVRXPPQPN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 310220   

TargetHistone-lysine N-methyltransferase EZH2(Human)
Epizyme

US Patent
LigandPNGBDBM310220(US10150759, Compound 2)
Affinity DataIC50: 7.10E+3nMAssay Description:The assays were all performed in a buffer consisting of 20 mM bicine (pH=7.6), 0.5 mM DTT, 0.005% BSG and 0.002% Tween20, prepared on the day of use....More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/9/2019
Entry Details
US Patent