BDBM310651 (5-(2,3-Dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-((3R,5S)-3,5-dihydroxypiperidine-1-carbonyl)thiazol-4-yl)((S)-4,4-difluoro-2-methylpyrrolidin-1-yl)methanone::US10150762, Example 8

SMILES C[C@H]1CC(F)(F)CN1C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(=O)N1C[C@@H](O)C[C@@H](O)C1

InChI Key InChIKey=UDVVEEZBUNKBJS-GARJFASQSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310651   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310651((5-(2,3-Dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataIC50:  11nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310651((5-(2,3-Dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydro...)
Affinity DataKd:  0.150nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent