BDBM310658 (4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2,3-dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)thiazol-2-yl)((3R,5S)-3,5-dihydroxypiperidin-1-yl)methanone::US10150762, Example 10

SMILES O[C@H]1C[C@@H](O)CN(C1)C(=O)c1nc(C(=O)N2C3CCC2CC3)c(s1)-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LYNOVUBPVXOVQL-BPNZPQAUSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310658   

TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310658((4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2,3...)
Affinity DataIC50:  13nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNuclear receptor ROR-gamma(Homo sapiens (Human))
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310658((4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2,3...)
Affinity DataKd:  2.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent