BDBM310663 ((3R,5S)-3,5-Dihydroxypiperidin-1-yl)(5-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-(trifluoromethyl)phenyl)-4-((S)-2-methylpyrrolidine-1-carbonyl)thiazol-2-yl)methanone::US10150762, Example 10/5

SMILES C[C@H]1CCCN1C(=O)c1nc(sc1-c1ccc(cc1C(F)(F)F)C(O)(C(F)(F)F)C(F)(F)F)C(=O)N1C[C@@H](O)C[C@@H](O)C1

InChI Key InChIKey=QKEHLMDMDOASCO-FPMFFAJLSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310663   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310663(((3R,5S)-3,5-Dihydroxypiperidin-1-yl)(5-(4-(1,1,1,...)
Affinity DataIC50:  14nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310663(((3R,5S)-3,5-Dihydroxypiperidin-1-yl)(5-(4-(1,1,1,...)
Affinity DataKd:  0.830nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent