BDBM310670 (S)-(5-(2,3-Dichloro-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-2-(2-imino-2-oxido-2-thia-6-azaspiro[3.3]heptane-6-carbonyl)thiazol-4-yl)(4,4-difluoro-2-methylpyrrolidin-1-yl)methanone::US10150762, Example 14/1
SMILES C[C@H]1CC(F)(F)CN1C(=O)c1nc(sc1-c1ccc(c(Cl)c1Cl)C(O)(C(F)(F)F)C(F)(F)F)C(=O)N1CC2(C1)CS(=N)(=O)C2
InChI Key InChIKey=STNJVEZVOSFJRB-JTQLQIEISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 310670
Affinity DataIC50: 15nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Affinity DataKd: 0.5nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair