BDBM310675 4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2-(difluoromethyl)-4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl)-N-(2-hydroxy-2-methylpropyl)thiazole-2-carboxamide::US10150762, Example 15/3

SMILES CC(C)(O)CNC(=O)c1nc(C(=O)N2C3CCC2CC3)c(s1)-c1ccc(cc1C(F)F)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=XLHDFVDHGMBJKQ-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310675   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310675(4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2-(d...)
Affinity DataIC50:  11nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310675(4-(7-Azabicyclo[2.2.11]heptane-7-carbonyl)-5-(2-(d...)
Affinity DataKd:  1.40nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent