BDBM310690 (S)-5-(4-(1,1,1,3,3,3-Hexafluoro-2-hydroxypropan-2-yl)-2-methylphenyl)-N-(2-hydroxy-2-methylpropyl)-4-(2-methylpyrrolidine-1-carbonyl)thiazole-2-carboxamide::US10150762, Example 19
SMILES C[C@H]1CCCN1C(=O)c1nc(sc1-c1ccc(cc1C)C(O)(C(F)(F)F)C(F)(F)F)C(=O)NCC(C)(C)O
InChI Key InChIKey=SKZVAPJZGNAQNI-ZDUSSCGKSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 310690
Affinity DataIC50: 14nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Affinity DataKd: 2.10nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair