BDBM310700 (S)-4-(4,4-difluoro-2-methylpyrrolidine-1-carbonyl)-5-(4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)-2-methoxyphenyl)-N-(2-hydroxy-2-methylpropyl)thiazole-2-carboxamide::US10150762, Example 24

SMILES COc1cc(ccc1-c1sc(nc1C(=O)N1CC(F)(F)C[C@@H]1C)C(=O)NCC(C)(C)O)C(O)(C(F)(F)F)C(F)(F)F

InChI Key InChIKey=RNUSAFOYIGEMHM-NSHDSACASA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 310700   

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310700((S)-4-(4,4-difluoro-2-methylpyrrolidine-1-carbonyl...)
Affinity DataIC50:  3.30nMAssay Description:Cells used in this assay were transiently co-transfected with three different plasmids, one expressing the GAL4-DNA binding domain (DBD)-RORγt f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent

TargetNuclear receptor ROR-gamma(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM310700((S)-4-(4,4-difluoro-2-methylpyrrolidine-1-carbonyl...)
Affinity DataKd:  0.840nMAssay Description:Project compounds were arranged in a pre-dosed mother plate (Greiner Bio-one) wherein compounds are serially diluted in 100% DMSO by 1:2 from a high ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent